INT213058

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Context Info
Confidence 0.05
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.15
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Apoa1) extracellular space (Apoa1) extracellular region (Apoa1)
cell adhesion (Scarb1) plasma membrane (Scarb1) nucleus (Apoa1)
Apoa1 (Mus musculus)
Scarb1 (Mus musculus)
Hdl1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 11 66.96 Quite High
chemokine 2 58.56 Quite High
cytokine 4 57.52 Quite High
metalloproteinase 6 5.00 Very Low Very Low Very Low
Tetrahydrobiopterin 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 137 100.00 Very High Very High Very High
INFLAMMATION 19 76.28 Quite High
Adhesions 18 18.56 Low Low
Atherosclerosis 10 5.00 Very Low Very Low Very Low
Apoptosis 7 5.00 Very Low Very Low Very Low
Coronary Artery Disease 6 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Atherosclerotic Plaque 3 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ApoA-I binding to the scavenger receptor-BI (SR-B1) is required for HDL activation of eNOS (Yuhanna et al 2001); however, eNOS is not activated by lipid-free ApoA-I.
ApoA-I Binding (binding) of SR-B1 Positive_regulation (required) of Positive_regulation (activation) of HDL associated with disorder of lipid metabolism
1) Confidence 0.05 Published 2005 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993938 Disease Relevance 1.15 Pain Relevance 0.12

General Comments

This test has worked.

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