INT213135

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Context Info
Confidence 0.02
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Scarb1) plasma membrane (Scarb1) cytoplasm (Scarb1)
Anatomy Link Frequency
liver 2
Scarb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 12 44.44 Quite Low
cytokine 2 8.24 Low Low
alcohol 14 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
Calcium channel 4 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Bile 2 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 30 98.24 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

12 93.68 High High
Atherosclerosis 72 76.28 Quite High
Stress 30 66.24 Quite High
Hypertension 76 65.60 Quite High
Coronary Artery Disease 6 64.24 Quite High
INFLAMMATION 16 44.44 Quite Low
Cardiovascular Disease 30 22.04 Low Low
Hypercholesterolemia 2 11.16 Low Low
Adhesions 12 5.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been suggested that AGEs interfere with reverse cholesterol transport by suppressing scavenger receptor B1 (SR-B1)-mediated uptake of cholesterol ester from HDL by liver and SR-B1-mediated cholesterol efflux from peripheral cells (Horiuchi et al 2003).
Negative_regulation (suppressing) of scavenger receptor B1 in liver associated with disorder of lipid metabolism
1) Confidence 0.02 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993980 Disease Relevance 0.93 Pain Relevance 0
It has been suggested that AGEs interfere with reverse cholesterol transport by suppressing scavenger receptor B1 (SR-B1)-mediated uptake of cholesterol ester from HDL by liver and SR-B1-mediated cholesterol efflux from peripheral cells (Horiuchi et al 2003).
Negative_regulation (suppressing) of SR-B1 in liver associated with disorder of lipid metabolism
2) Confidence 0.02 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993980 Disease Relevance 0.94 Pain Relevance 0

General Comments

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