INT213136

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.76
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Apob) transport (Apob) extracellular space (Apob)
extracellular region (Apob) endoplasmic reticulum (Apob) enzyme binding (Apob)
Anatomy Link Frequency
macrophage 1
Apob (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 6 82.32 Quite High
Bioavailability 2 54.72 Quite High
tolerance 2 46.80 Quite Low
alcohol 7 5.00 Very Low Very Low Very Low
Angina 5 5.00 Very Low Very Low Very Low
aspirin 3 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 28 100.00 Very High Very High Very High
Cardiovascular Disease 23 99.00 Very High Very High Very High
Insulin Resistance 47 98.60 Very High Very High Very High
Increased Venous Pressure Under Development 1 90.16 High High
Hypertension 43 87.16 High High
Diabetes Mellitus 29 83.28 Quite High
INFLAMMATION 8 82.32 Quite High
Metabolic Syndrome 5 81.60 Quite High
Hypercholesterolemia 1 78.16 Quite High
Atherosclerosis 36 76.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Alterations to lysine residues of apolipoprotein B of LDL result in a decreased binding by LDL receptors and an increased stimulation of macrophage scavenger receptors (Witztum and Steinberg 1991; Haberland et al 1992; Horiuchi et al 2003).
apolipoprotein B Binding (binding) of in macrophage associated with disorder of lipid metabolism
1) Confidence 0.03 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993980 Disease Relevance 0.71 Pain Relevance 0.07
This has indicated that apolipoprotein B is associated with the development of cardiovascular disease.
apolipoprotein B Binding (associated) of associated with cardiovascular disease and disorder of lipid metabolism
2) Confidence 0.01 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2733993 Disease Relevance 1.90 Pain Relevance 0

General Comments

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