INT213214

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 4.59
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (ASAP2) plasma membrane (ASAP2) cytoplasm (ASAP2)
Anatomy Link Frequency
pulmonary artery 2
mitral valve 1
ASAP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 16 82.40 Quite High
cytokine 4 67.40 Quite High
cva 36 67.28 Quite High
Inflammation 4 67.00 Quite High
agonist 4 61.56 Quite High
headache 12 5.00 Very Low Very Low Very Low
fibrosis 8 5.00 Very Low Very Low Very Low
Calcium channel 8 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 36 99.28 Very High Very High Very High
Hypoxia 52 98.96 Very High Very High Very High
Pulmonary Hypertension 328 98.64 Very High Very High Very High
Increased Venous Pressure Under Development 44 91.92 High High
Pressure Volume 2 Under Development 16 89.12 High High
Impotence 12 75.16 Quite High
Cv General 3 Under Development 12 67.28 Quite High
INFLAMMATION 4 67.00 Quite High
Hemoglobinopathy 4 62.88 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 24 61.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect was augmented by exercise but significantly blunted by treatment with a one time dose of 50mg of sildenafil (increase in mPAP: placebo group sea level hypoxia rest +75%, exercise +145%; Everest rest +57%, exercise +92%; sildenafil sea level hypoxia rest +26%, exercise +108%; Everest rest +26%, exercise +57%).
Positive_regulation (increase) of mPAP associated with hypoxia
1) Confidence 0.01 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994020 Disease Relevance 0.88 Pain Relevance 0.15
Pulmonary hypertension is a general term for a disease process resulting in a progressive increase in the mean pulmonary artery pressure (mPAP) (mPAP ?
Positive_regulation (increase) of mPAP in pulmonary artery associated with pulmonary hypertension and disease
2) Confidence 0.01 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994020 Disease Relevance 1.66 Pain Relevance 0.07
Pulmonary hypertension is a general term for a disease process resulting in a progressive increase in the mean pulmonary artery pressure (mPAP) (mPAP ?
Positive_regulation (increase) of mPAP in pulmonary artery associated with pulmonary hypertension and disease
3) Confidence 0.01 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994020 Disease Relevance 1.65 Pain Relevance 0.07
In a third, patientsÂ’ status post mitral valve surgery or left ventricular assist device (LVAD) placement who received sildenafil for elevated PAP had significant improvement in MAP, mPAP, and PVRI.
Positive_regulation (improvement) of mPAP in mitral valve
4) Confidence 0.01 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994020 Disease Relevance 0.39 Pain Relevance 0.03

General Comments

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