INT213217

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Context Info
Confidence 0.32
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.03
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PAH) small molecule metabolic process (PAH) cellular nitrogen compound metabolic process (PAH)
Anatomy Link Frequency
connective tissue 2
PAH (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 6 100.00 Very High Very High Very High
cva 10 82.76 Quite High
antagonist 19 43.60 Quite Low
Bile 4 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Hypertension 153 100.00 Very High Very High Very High
Pulmonary Fibrosis 2 100.00 Very High Very High Very High
Fibrosis 8 99.92 Very High Very High Very High
Coronary Heart Disease 3 99.76 Very High Very High Very High
Pulmonary Disease 4 99.20 Very High Very High Very High
Disease 28 96.24 Very High Very High Very High
Interstitial Lung Diseases 3 87.92 High High
Cv General 3 Under Development 4 82.76 Quite High
Dyspnea 6 78.20 Quite High
Hypoxia 17 76.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pulmonary fibrosis associated PH
Negative_regulation (fibrosis) of PH Binding (associated) of associated with fibrosis, pulmonary hypertension and pulmonary fibrosis
1) Confidence 0.32 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994020 Disease Relevance 1.27 Pain Relevance 0.19
Data from subgroup analyses did not exhibit a clinically relevant treatment effect in patients with PAH associated with CHD.70 In contrast, the subgroup of patients with PAH associated with connective tissue disease (CTD) showed an increased 6MWD with sitaxentan treatment.82,83


Negative_regulation (effect) of PAH Binding (associated) of in connective tissue associated with pulmonary hypertension, disease and coronary heart disease
2) Confidence 0.17 Published 2008 Journal European Heart Journal Section Body Doc Link PMC2515885 Disease Relevance 0.76 Pain Relevance 0

General Comments

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