INT213219

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Context Info
Confidence 0.14
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ALDH7A1) small molecule metabolic process (ALDH7A1) cytoplasm (ALDH7A1)
cytosol (ALDH7A1) oxidoreductase activity (ALDH7A1) nucleus (ALDH7A1)
ALDH7A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 1 86.72 High High
Pain 1 67.52 Quite High
headache 3 67.00 Quite High
tolerance 4 56.16 Quite High
Potency 1 51.92 Quite High
Calcium channel 2 30.04 Quite Low
nud 1 19.84 Low Low
cva 9 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Hypertension 82 97.96 Very High Very High Very High
Thrombosis 6 74.76 Quite High
Infection 2 74.28 Quite High
Pain 1 67.52 Quite High
Headache 3 67.00 Quite High
Pressure Volume 2 Under Development 4 66.60 Quite High
Increased Venous Pressure Under Development 11 65.60 Quite High
Cv General 4 Under Development 9 51.84 Quite High
Disorders Of Creatine Metabolism 1 44.80 Quite Low
Cirrhosis 2 41.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sildenafil is a selective and potent inhibitor of PDE type 5 which specifically degrades cyclic guanosine monophosphate and is found in high concentrations in pulmonary arteries and the corpora cavernosum (Rabe et al 1994; Ahn et al 1991; Boolell et al 1996; Pauvert et al 2002; Pauvert et al 2003).
Protein_catabolism (degrades) of PDE
1) Confidence 0.14 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994020 Disease Relevance 0.70 Pain Relevance 0.23

General Comments

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