INT213264

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Context Info
Confidence 0.16
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.77
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (INS, IGF1) extracellular region (INS, IGF1) signal transduction (IGF1)
small molecule metabolic process (INS) carbohydrate metabolic process (INS) cell-cell signaling (INS)
Anatomy Link Frequency
smooth muscle 2
INS (Homo sapiens)
IGF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Serotonin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 12 98.28 Very High Very High Very High
Hypertrophy 1 96.40 Very High Very High Very High
Syndrome 8 90.96 High High
Hyperinsulinism 9 88.28 High High
Polycystic Ovary Syndrome 83 86.64 High High
Obesity 43 83.44 Quite High
Insulin Resistance 16 74.20 Quite High
Coronary Heart Disease 7 50.48 Quite High
Dyslipidemia /

Combined Dyslipidemia

9 48.48 Quite Low
Disorder Of Lipid Metabolism 5 32.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Insulin also stimulates the release of IGF-1 that may contribute to the development of hypertension by causing vascular smooth muscle hypertrophy.
Insulin Positive_regulation (stimulates) of Localization (release) of IGF-1 in smooth muscle associated with hypertrophy and hypertension
1) Confidence 0.16 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994046 Disease Relevance 1.77 Pain Relevance 0

General Comments

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