INT213410

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Context Info
Confidence 0.71
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.89
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TKT) small molecule metabolic process (TKT) nucleolus (TKT)
peroxisome (TKT) nucleus (TKT) carbohydrate metabolic process (TKT)
TKT (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 95 97.12 Very High Very High Very High
positron emission tomography 27 70.80 Quite High
Inflammation 42 37.92 Quite Low
cytokine 84 5.00 Very Low Very Low Very Low
Central nervous system 42 5.00 Very Low Very Low Very Low
Pain 38 5.00 Very Low Very Low Very Low
Nerve growth factor 20 5.00 Very Low Very Low Very Low
Peripheral nervous system 16 5.00 Very Low Very Low Very Low
Multiple sclerosis 14 5.00 Very Low Very Low Very Low
chemokine 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cold Sores 734 100.00 Very High Very High Very High
Cancer 405 99.12 Very High Very High Very High
Epstein-barr Virus 1 90.80 High High
Viral Infection 16 87.88 High High
Infection 184 87.24 High High
Disease 71 73.08 Quite High
Suicidal Behaviour 6 71.76 Quite High
Adverse Drug Reaction 2 63.88 Quite High
Hepatotoxicity 1 53.20 Quite High
Bacterial Infection 12 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Later in life, these men returned to the community of their birth, but the substantial number of years away from their native environment and traditions was detrimental to their level of TK.
Localization (level) of TK
1) Confidence 0.71 Published 2008 Journal J Ethnobiol Ethnomed Section Body Doc Link PMC2275234 Disease Relevance 0 Pain Relevance 0
The main advantage of the use of HSV-1-TK in gene therapy protocols is the fact that this gene can be used as an imaging gene and as a therapeutic gene.
Localization (use) of TK associated with cold sores and imagery
2) Confidence 0.17 Published 2010 Journal The Open Virology Journal Section Body Doc Link PMC2936037 Disease Relevance 0.46 Pain Relevance 0.29
These vectors retained an intact viral tk gene and contained a lac Z insertional mutation within the gene encoding RR, while MGH-1 bore additional mutation at both ?
Localization (retained) of tk
3) Confidence 0.17 Published 2010 Journal The Open Virology Journal Section Body Doc Link PMC2936037 Disease Relevance 0.83 Pain Relevance 0.24
When coupled with a radioisotope, radiolabeled FIAU (rFIAU) can be detected using SPECT or PET to localize TK-expressing cells in humans.
Localization (localize) of TK
4) Confidence 0.12 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1994593 Disease Relevance 0.60 Pain Relevance 0.08

General Comments

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