INT213434

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.64
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 4.33
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

methyltransferase activity (HNMT) nucleolus (HNMT) nucleus (HNMT)
response to stress (HNMT) cytoplasm (HNMT)
Anatomy Link Frequency
Visceral 3
HNMT (Homo sapiens)
Pain Link Frequency Relevance Heat
Antihistamine 6 97.08 Very High Very High Very High
agonist 6 88.44 High High
cINOD 6 51.76 Quite High
Inflammation 15 48.88 Quite Low
cytokine 9 46.64 Quite Low
aspirin 6 33.08 Quite Low
Inflammatory response 9 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
Neuropeptide 3 5.00 Very Low Very Low Very Low
Dismenorea 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 93 99.24 Very High Very High Very High
Urticaria 51 98.80 Very High Very High Very High
Asthma 54 98.72 Very High Very High Very High
Microphthalmia 3 78.20 Quite High
Autoimmune Disease 3 78.16 Quite High
Pressure Volume 2 Under Development 3 76.32 Quite High
Heart Rate Under Development 3 75.28 Quite High
Congenital Anomalies 15 72.92 Quite High
Pruritus 3 69.12 Quite High
Drug Hypersensitivity 21 61.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Histamine is metabolized primarily by histamine N-methyltransferase (HNMT) and diamine oxidase (5).
Gene_expression (metabolized) of histamine N-methyltransferase
1) Confidence 0.64 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2782188 Disease Relevance 1.12 Pain Relevance 0.14
Histamine is metabolized primarily by HNMT and diamine oxidase in mammals and the effects of histamine are mediated by three pharmacologically defined receptors termed H1 and H2 (5, 21).
Gene_expression (metabolized) of HNMT
2) Confidence 0.64 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2782188 Disease Relevance 1.18 Pain Relevance 0.05
Histamine is metabolized primarily by histamine N-methyltransferase (HNMT) and diamine oxidase (5).
Gene_expression (metabolized) of HNMT
3) Confidence 0.64 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2782188 Disease Relevance 1.12 Pain Relevance 0.14
Visceral SMCs also preferentially expressed Histamine N-methyltransferase (HNMT), an essential enzyme that regulates histamine levels in tissues by catalyzing its inactivation by N-methylation [44] (Figure 2B).
Gene_expression (expressed) of Histamine N-methyltransferase in Visceral
4) Confidence 0.64 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1994710 Disease Relevance 0.27 Pain Relevance 0.04
Visceral SMCs also preferentially expressed Histamine N-methyltransferase (HNMT), an essential enzyme that regulates histamine levels in tissues by catalyzing its inactivation by N-methylation [44] (Figure 2B).
Gene_expression (expressed) of HNMT in Visceral
5) Confidence 0.64 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1994710 Disease Relevance 0.27 Pain Relevance 0.04
Preferential expression of HNMT in all visceral SMCs suggests a strong, intrinsic ability of these cells to catalyze the local degradation of histamine.
Gene_expression (expression) of HNMT in visceral
6) Confidence 0.64 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1994710 Disease Relevance 0.36 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox