INT213436

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Context Info
Confidence 0.53
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.66
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (FOXP1) nucleus (FOXP1) intracellular (FOXP1)
embryo development (FOXP1) transcription factor binding (FOXP1) cytoplasm (FOXP1)
Anatomy Link Frequency
lung 2
FOXP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 4 80.48 Quite High
cytokine 2 80.04 Quite High
Inflammation 8 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
Dismenorea 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Atherosclerosis 18 96.68 Very High Very High Very High
Increased Venous Pressure Under Development 6 92.88 High High
Stress Incontinence 8 68.64 Quite High
Cancer 72 5.00 Very Low Very Low Very Low
Hypoxia 38 5.00 Very Low Very Low Very Low
Breast Cancer 24 5.00 Very Low Very Low Very Low
Vascular System Injuries 16 5.00 Very Low Very Low Very Low
Disease 16 5.00 Very Low Very Low Very Low
INFLAMMATION 14 5.00 Very Low Very Low Very Low
Injury 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SMC samples derived from lung tissue (pulmonary artery and bronchus) expressed a common set of genes (Figure 3C), notably including the genes encoding FOXP1, a transcriptional repressor expressed in lung mesenchyme that modulates gene expression in lung tissue [49], and endothelin receptor A (EDNRA), the high-affinity receptor for EDN1, a peptide hormone that stimulates vasoconstriction and proliferation of SMCs [50].


Gene_expression (expressed) of FOXP1 in lung associated with increased venous pressure under development
1) Confidence 0.53 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1994710 Disease Relevance 0.33 Pain Relevance 0.08
SMC samples derived from lung tissue (pulmonary artery and bronchus) expressed a common set of genes (Figure 3C), notably including the genes encoding FOXP1, a transcriptional repressor expressed in lung mesenchyme that modulates gene expression in lung tissue [49], and endothelin receptor A (EDNRA), the high-affinity receptor for EDN1, a peptide hormone that stimulates vasoconstriction and proliferation of SMCs [50].


Gene_expression (expressed) of FOXP1 in lung associated with increased venous pressure under development
2) Confidence 0.41 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1994710 Disease Relevance 0.33 Pain Relevance 0.08

General Comments

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