INT213535

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Context Info
Confidence 0.62
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.69
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Phox2b) DNA binding (Phox2b)
Anatomy Link Frequency
ganglia 2
brainstem 1
nucleus 1
Phox2b (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 3 99.04 Very High Very High Very High
Hippocampus 89 97.24 Very High Very High Very High
Catecholamine 1 96.00 Very High Very High Very High
medulla 10 94.04 High High
Locus ceruleus 8 91.04 High High
imagery 18 81.96 Quite High
Neurotransmitter 2 64.92 Quite High
trigeminal ganglion 1 32.08 Quite Low
bDMF 49 5.00 Very Low Very Low Very Low
Nerve growth factor 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 5 98.20 Very High Very High Very High
Injury 43 96.92 Very High Very High Very High
Syndrome 32 96.32 Very High Very High Very High
Targeted Disruption 45 94.76 High High
Central Hypoventilation Syndrome 108 84.64 Quite High
Sleep Disorders 73 73.04 Quite High
Hypoventilation 6 72.24 Quite High
Frailty 1 70.40 Quite High
Cerebrovascular Disease 2 65.80 Quite High
Hypoxia 21 58.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to Ngn2, the homeodomain transcription factors, Phox2a and Phox2b, regulate pan-neuronal fate in the geniculate and petrosal ganglia.
Transcription (transcription) of Phox2b in ganglia
1) Confidence 0.62 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1995452 Disease Relevance 0.17 Pain Relevance 0
-hydroxylase) and the transcription factors PHOX2A and PHOX2B which are involved in the development of this nucleus [23].
Transcription (transcription) of PHOX2B in nucleus
2) Confidence 0.51 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2617764 Disease Relevance 0.13 Pain Relevance 0.21
The mouse equivalent Phox2b transcription factor is expressed in the pyramidal and granule cell layers of the hippocampus [19], as well as the well-described targets in visceral ganglia and brainstem [38], [47].
Transcription (transcription) of Phox2b in ganglia associated with medulla and hippocampus
3) Confidence 0.48 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2713409 Disease Relevance 1.20 Pain Relevance 0.14
The mouse equivalent Phox2b transcription factor is expressed in the pyramidal and granule cell layers of the hippocampus [19], as well as the well-described targets in visceral ganglia and brainstem [38], [47].
Transcription (transcription) of Phox2b in brainstem associated with medulla and hippocampus
4) Confidence 0.16 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2713409 Disease Relevance 1.20 Pain Relevance 0.14

General Comments

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