INT213561

Context Info Confidence 0.24 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0.17

extracellular region (Ngf, Sema3a) cell differentiation (Sema3a) signal transduction (Ngf) extracellular space (Ngf)

Anatomy Link Frequency neurons 2 Ngf (Mus musculus) Sema3a (Mus musculus)

Pain Link Frequency Relevance Heat Nerve growth factor 6 100.00 bDMF 49 99.20 addiction 3 5.00 Spinal cord 2 5.00 medulla 2 5.00 nociceptor 2 5.00 antagonist 2 5.00 trigeminal ganglion 1 5.00 Central nervous system 1 5.00 Neurotransmitter 1 5.00

Disease Link Frequency Relevance Heat Ganglion Cysts 44 82.40 Death 7 5.00 Apoptosis 3 5.00 Targeted Disruption 2 5.00 Pain 1 5.00 Pressure And Volume Under Development 1 5.00 Frailty 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

NGF, on the other hand, has been shown to reduce the sensitivity of somatosensory neurons to Sema3A [77,81].

NGF Negative_regulation (reduce) of Regulation (sensitivity) of Sema3A in neurons associated with nerve growth factor

1) Confidence 0.24 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1995452 Disease Relevance 0.08 Pain Relevance 0.17

General Comments

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