INT213608

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Context Info
Confidence 0.22
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (PER2, CLOCK) signal transducer activity (PER2, CLOCK) nucleus (PER2, CLOCK)
protein binding transcription factor activity (PER2) transferase activity, transferring acyl groups (CLOCK) DNA binding (CLOCK)
PER2 (Homo sapiens)
CLOCK (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 2 76.20 Quite High
Neuropeptide 6 5.00 Very Low Very Low Very Low
dopamine receptor 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Locus ceruleus 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sleep Disorders 55 99.00 Very High Very High Very High
Idiopathic Hypersomnolence 1 86.96 High High
Coronary Artery Disease 1 45.80 Quite Low
Diabetes Mellitus 1 44.52 Quite Low
Hypertension 1 43.56 Quite Low
Chronobiology Disorders 2 11.76 Low Low
Hypersomnia 1 6.24 Low Low
Apnoea 3 5.00 Very Low Very Low Very Low
Snoring 3 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Polymorphisms in the human period 2 (PER2) and casein kinase 1d (CSNK1D) genes, known elements of the circadian molecular clock, are associated with autosomal dominant advanced sleep phase syndrome in isolated families [25,26].
period Binding (associated) of clock associated with sleep disorders
1) Confidence 0.22 Published 2007 Journal BMC Med Genet Section Body Doc Link PMC1995620 Disease Relevance 0.65 Pain Relevance 0.04

General Comments

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