INT213651

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Context Info
Confidence 0.36
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (HCRT) cytoplasm (HCRT)
HCRT (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 19 97.84 Very High Very High Very High
isoflurane 15 90.80 High High
Thalamus 2 74.60 Quite High
potassium channel 5 72.96 Quite High
Neurotransmitter 1 72.04 Quite High
medulla 2 58.48 Quite High
Central nervous system 13 43.48 Quite Low
halothane 21 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Eae 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sleep Disorders 21 99.68 Very High Very High Very High
Targeted Disruption 3 95.72 Very High Very High Very High
Delayed Emergence From Anesthesia 1 89.52 High High
Shock 3 82.80 Quite High
Inborn Genetic Diseases 14 50.00 Quite Low
Unconsciousness 14 50.00 Quite Low
Disease 31 33.00 Quite Low
Cognitive Disorder 2 19.36 Low Low
Retina Disease 10 8.72 Low Low
Coagulation Disorder 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Narcolepsy with cataplexy is caused by a derangement of orexin (also known as hypocretin) signaling [46], [47].
orexin Binding (derangement) of associated with sleep disorders
1) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912772 Disease Relevance 0.37 Pain Relevance 0.52
Hcrt and its receptors encoded by Hcrtr-1 and Hcrtr-2 were sequenced in human patients with narcolepsy and a substitution mutation in Hcrt of a single patient was identified (Peyron et al. 2000).
Hcrt Binding (receptors) of associated with sleep disorders
2) Confidence 0.19 Published 2007 Journal Mamm Genome Section Body Doc Link PMC1998873 Disease Relevance 0.71 Pain Relevance 0.04

General Comments

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