INT213659

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Context Info
Confidence 0.74
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 3.75
Pain Relevance 0.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (RIT1) plasma membrane (RIT1) GTPase activity (RIT1)
Anatomy Link Frequency
Teeth 1
RIT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
positron emission tomography 174 100.00 Very High Very High Very High
imagery 81 99.24 Very High Very High Very High
Inflammation 18 58.40 Quite High
palliative 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 302 99.98 Very High Very High Very High
Glioma 39 99.88 Very High Very High Very High
Recurrence 95 97.08 Very High Very High Very High
Ovarian Cancer 126 95.64 Very High Very High Very High
Disease 28 85.36 High High
Soft Tissue Infections 6 74.56 Quite High
Radiation Sickness 9 71.44 Quite High
Malignant Neoplastic Disease 12 66.08 Quite High
Glioblastoma 18 61.92 Quite High
Anaplastic Astrocytoma 15 61.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Likewise, in our study, high expression of Ras inhibitor 1 (RIN1) and low expression of Ras-like without CAAX1 (RIT1) were associated with better overall survival, which is in agreement with previous work by others showing that activated Ras contributes to the maintenance and growth of ovarian carcinomas [38].
Gene_expression (expression) of CAAX1 associated with ovarian cancer
1) Confidence 0.74 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2634794 Disease Relevance 0.68 Pain Relevance 0
Likewise, in our study, high expression of Ras inhibitor 1 (RIN1) and low expression of Ras-like without CAAX1 (RIT1) were associated with better overall survival, which is in agreement with previous work by others showing that activated Ras contributes to the maintenance and growth of ovarian carcinomas [38].
Gene_expression (expression) of RIT1 associated with ovarian cancer
2) Confidence 0.74 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2634794 Disease Relevance 0.69 Pain Relevance 0
In 20 patients, serial FET PET and MRI scans were performed preceding every RIT cycle and at 3-month intervals after the end of RIT in order to detect tumour recurrence and to monitor the therapeutic effects.
Gene_expression (cycle) of RIT associated with cancer, positron emission tomography, imagery and recurrence
3) Confidence 0.24 Published 2006 Journal Eur J Nucl Med Mol Imaging Section Body Doc Link PMC1998889 Disease Relevance 0.74 Pain Relevance 0.33
Twenty-four patients with malignant gliomas were followed up with serial FET PET scans during and/or after intracavitary RIT.
Gene_expression (followed) of RIT associated with positron emission tomography and glioma
4) Confidence 0.24 Published 2006 Journal Eur J Nucl Med Mol Imaging Section Body Doc Link PMC1998889 Disease Relevance 1.10 Pain Relevance 0.35
Using the threshold value of 2.4 (as determined by ROC analyses) and regardless of the uptake pattern, FET PET was able to distinguish with high discriminatory power between tumour progression during or after RIT and therapy-induced benign changes: in 21/24 patients there was accurate assessment in all serial PET scans, while in the remaining three patients there was false negative assessment, with TUmax/BG ratios of 2.0, 2.1 and 2.2 respectively.
Gene_expression (progression) of RIT associated with cancer and positron emission tomography
5) Confidence 0.24 Published 2006 Journal Eur J Nucl Med Mol Imaging Section Body Doc Link PMC1998889 Disease Relevance 0.54 Pain Relevance 0.24
Rinsing Pop Colas with and without Teeth
Gene_expression (Rinsing) of with and without Teeth in Teeth
6) Confidence 0.06 Published 2010 Journal International Journal of Dentistry Section Body Doc Link PMC2997506 Disease Relevance 0 Pain Relevance 0

General Comments

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