INT213763

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Context Info
Confidence 0.39
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Tfeb) DNA binding (Tfeb) cytoplasm (Tfeb)
Anatomy Link Frequency
mast cell 2
Tfeb (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 43 87.68 High High
interstitial cystitis 4 51.68 Quite High
Inflammatory mediators 1 51.36 Quite High
cytokine 1 43.76 Quite Low
Inflammatory stimuli 3 39.28 Quite Low
Inflammatory response 7 5.00 Very Low Very Low Very Low
substance P 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cystitis 8 92.00 High High
INFLAMMATION 54 87.68 High High
Adhesions 1 68.08 Quite High
Interstitial Cystitis 4 51.68 Quite High
Microphthalmia 23 17.24 Low Low
Mastocytosis 1 16.40 Low Low
Overactive Bladder 11 5.00 Very Low Very Low Very Low
Renal Cancer 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Bladder Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our present findings further emphasize that products of mast cells such as tryptase inducing activation of PARs can lead to increased activity of transcription factors such as TFEB that play a fundamental role in mast cell survival.
Positive_regulation (lead) of Positive_regulation (increased) of TFEB in mast cell
1) Confidence 0.39 Published 2007 Journal BMC Immunol Section Body Doc Link PMC2000913 Disease Relevance 0.70 Pain Relevance 0.23

General Comments

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