INT213764

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Context Info
Confidence 0.21
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.37
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (F2rl3) plasma membrane (F2rl3) signal transducer activity (F2rl3)
Anatomy Link Frequency
neuronal 1
urinary bladder 1
F2rl3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 55 99.00 Very High Very High Very High
agonist 15 59.96 Quite High
Inflammatory response 7 52.24 Quite High
substance P 8 47.32 Quite Low
Calcitonin gene-related peptide 20 5.00 Very Low Very Low Very Low
nociceptor 16 5.00 Very Low Very Low Very Low
Nerve growth factor 14 5.00 Very Low Very Low Very Low
qutenza 14 5.00 Very Low Very Low Very Low
Neuropeptide 12 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 67 99.00 Very High Very High Very High
Microphthalmia 23 58.12 Quite High
Hypersensitivity 1 53.24 Quite High
Nociception 21 50.00 Quite Low
Mastocytosis 1 47.12 Quite Low
Dislocations 2 7.16 Low Low
Overactive Bladder 11 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
Cystitis 8 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although thrombin is a recognized physiological activator of PAR1 and PAR4, the endogenous enzymes responsible for activating PAR2 in urinary bladder are not known.
PAR4 Binding (recognized) of in urinary bladder
1) Confidence 0.21 Published 2007 Journal BMC Immunol Section Body Doc Link PMC2000913 Disease Relevance 0.32 Pain Relevance 0.11
Signal intensity for PAR1, PAR2 and PAR4 was determined by dividing grain counts by the area of the neuronal profile.
PAR4 Binding (intensity) of in neuronal
2) Confidence 0.14 Published 2010 Journal Mol Pain Section Body Doc Link PMC2956715 Disease Relevance 0.05 Pain Relevance 0

General Comments

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