INT213777

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.58
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.36
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Kit) cell differentiation (Kit) extracellular space (Kit)
plasma membrane (Kit) nucleus (Kit) kinase activity (Kit)
Anatomy Link Frequency
bladder 2
mast cell 2
Kit (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 43 100.00 Very High Very High Very High
Inflammatory response 7 79.60 Quite High
Pain 4 5.00 Very Low Very Low Very Low
interstitial cystitis 4 5.00 Very Low Very Low Very Low
abdominal pain 3 5.00 Very Low Very Low Very Low
Inflammatory stimuli 3 5.00 Very Low Very Low Very Low
substance P 3 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 54 100.00 Very High Very High Very High
Cystitis 8 94.24 High High
Mastocytosis 49 92.32 High High
Hematological Disease 1 87.20 High High
Cutaneous Mastocytosis 7 72.64 Quite High
Overactive Bladder 11 66.96 Quite High
Disease 17 58.32 Quite High
Increased Venous Pressure Under Development 3 56.56 Quite High
Systemic Mastocytosis 27 50.72 Quite High
Microphthalmia 23 6.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In neoplastic mast cell lines, valine or tyrosine substitution for an aspartate in c-kit codon 816 results in constitutive phosphorylation and activation of KIT[6].
Positive_regulation (results) of Phosphorylation (phosphorylation) of KIT in mast cell
1) Confidence 0.58 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2292130 Disease Relevance 0.62 Pain Relevance 0
Absence of PAR-induced bladder inflammation in c-kit-deficient mice
Positive_regulation (induced) of Phosphorylation (inflammation) of c-kit in bladder associated with inflammation
2) Confidence 0.32 Published 2007 Journal BMC Immunol Section Body Doc Link PMC2000913 Disease Relevance 0.73 Pain Relevance 0.26

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox