INT213867

Context Info Confidence 0.13 First Reported 2007 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.27 Pain Relevance 0

cell proliferation (ERF) nucleus (ERF)

ERF (Homo sapiens)

Pain Link Frequency Relevance Heat analgesia 2 5.00 Pain 2 5.00 Neuropeptide 1 5.00

Disease Link Frequency Relevance Heat Acquired Immune Deficiency Syndrome Or Hiv Infection 30 98.90 Targeted Disruption 23 44.44 Helminth Infection 3 5.00 Stress 3 5.00 Pain 2 5.00 Malaria 2 5.00 Communicable Diseases 1 5.00 Death 1 5.00 Disease 1 5.00 Cancer 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In the WHO HIV and infant feeding guidelines the AFASS-term has been linked with ERF.

ERF Binding (linked) of associated with acquired immune deficiency syndrome or hiv infection

1) Confidence 0.13 Published 2010 Journal Int Breastfeed J Section Body Doc Link PMC2987848 Disease Relevance 0.27 Pain Relevance 0

Based on these findings and the absence of nPE2 in nonmammalian vertebrates, we conclude that nPE2 is a mammalian novelty that appeared in an ancestor to all extant mammals, prior to 170 million years ago (MYA) [22].

nPE2 Neg (absence) Binding (absence) of

2) Confidence 0.01 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC2000970 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.