INT213901

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Context Info
Confidence 0.52
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (EGFR, ERBB2) cell proliferation (EGFR, ERBB2) signal transduction (EGFR, ERBB2)
plasma membrane (EGFR, ERBB2) nucleus (EGFR, ERBB2) endosome (EGFR)
EGFR (Homo sapiens)
ERBB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 4 81.56 Quite High
Pain 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 42 99.72 Very High Very High Very High
Cancer 21 65.16 Quite High
Advanced Or Metastatic Breast Cancer 10 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Recurrence 3 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Metastasis 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Fatigue 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Data also support the use of EGFR tyrosine kinase inhibitors in combination with HER2 antibodies, such as trastuzumab, against breast tumors that express EGFR and high levels of HER2 [37].
EGFR Positive_regulation (levels) of HER2 associated with breast cancer
1) Confidence 0.52 Published 2007 Journal Breast Cancer Res Treat Section Body Doc Link PMC2001220 Disease Relevance 0.41 Pain Relevance 0.04

General Comments

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