INT213911

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Context Info
Confidence 0.32
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.67
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NCOA3) small molecule metabolic process (NCOA3) Golgi apparatus (NCOA3)
nucleolus (NCOA3) nucleus (NCOA3) transferase activity, transferring acyl groups (NCOA3)
Anatomy Link Frequency
MCF-7 4
NCOA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 8 99.04 Very High Very High Very High
Pain 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 84 99.50 Very High Very High Very High
Apoptosis 2 57.36 Quite High
Disease 14 26.64 Quite Low
Cancer 42 11.68 Low Low
Advanced Or Metastatic Breast Cancer 20 5.00 Very Low Very Low Very Low
Recurrence 6 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low
Fatigue 2 5.00 Very Low Very Low Very Low
Headache 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Shou et al. [4] reported that tamoxifen behaves as an agonist in MCF-7 breast cancer cells that express high levels of the coactivator AIB1 (src3) and HER2, resulting in de novo resistance.
Positive_regulation (levels) of Positive_regulation (levels) of src3 in MCF-7 associated with breast cancer and agonist
1) Confidence 0.32 Published 2007 Journal Breast Cancer Res Treat Section Body Doc Link PMC2001220 Disease Relevance 0.34 Pain Relevance 0.05
Shou et al. [4] reported that tamoxifen behaves as an agonist in MCF-7 breast cancer cells that express high levels of the coactivator AIB1 (src3) and HER2, resulting in de novo resistance.
Positive_regulation (levels) of Positive_regulation (levels) of AIB1 in MCF-7 associated with breast cancer and agonist
2) Confidence 0.32 Published 2007 Journal Breast Cancer Res Treat Section Body Doc Link PMC2001220 Disease Relevance 0.33 Pain Relevance 0.05

General Comments

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