INT213950

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Context Info
Confidence 0.75
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 6
Disease Relevance 1.14
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (DNAJC5) protein folding (DNAJC5) cell death (DNAJC5)
plasma membrane (DNAJC5)
Anatomy Link Frequency
sensilla 2
bands 1
DNAJC5 (Homo sapiens)
Pain Link Frequency Relevance Heat
drug abuse 1 71.84 Quite High
alcohol 1 70.16 Quite High
Potency 1 62.24 Quite High
Pain 12 47.24 Quite Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malaria 27 97.78 Very High Very High Very High
Infertility 1 96.64 Very High Very High Very High
Acute Disease 1 84.84 Quite High
Disease 1 81.28 Quite High
Hypersensitivity 1 80.96 Quite High
Influenza Virus Infection 9 80.24 Quite High
Immunodeficiency 1 79.88 Quite High
Infection 1 77.60 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 77.16 Quite High
Intravenous Substance Abuse 1 71.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, SinvCSP was specifically expressed in the all polygyne workers investigated.
Gene_expression (expressed) of CSP
1) Confidence 0.75 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2582448 Disease Relevance 0 Pain Relevance 0
As it has been demonstrated for a chemosensory protein from the Argentine ant, Linepithema humile, LhumCSP [16], SinvCSP is antennae-specific, and expressed in the last two segments housing olfactory sensilla.
Gene_expression (expressed) of CSP in sensilla
2) Confidence 0.75 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2582448 Disease Relevance 0 Pain Relevance 0
We analyzed antennal extracts from North Carolina workers and found three fast migrating bands, GP-9b, GP-9B, and SinvCSP (data not shown).
Gene_expression (bands) of CSP in bands
3) Confidence 0.65 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2582448 Disease Relevance 0 Pain Relevance 0
Within the antennae, expression of SinvCSP is restricted to the last two segments, which are known to house olfactory sensilla.



Gene_expression (expression) of CSP in sensilla
4) Confidence 0.58 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2582448 Disease Relevance 0 Pain Relevance 0
In marked contrast to GP-9s, a chemosensory protein, SinvCSP, is demonstrated to be specifically expressed in the antennae.
Gene_expression (expressed) of CSP
5) Confidence 0.58 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2582448 Disease Relevance 0 Pain Relevance 0
Two virosome-formulated P. falciparum malaria vaccines PEV301 (incorporating the AMA-1 derived PE-peptide conjugate AMA49-C1) and PEV302 (incorporating the CSP derived PE-peptide conjugate UK-39) were produced according to the rules of GMP.
Gene_expression (produced) of CSP associated with malaria
6) Confidence 0.01 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2001290 Disease Relevance 1.14 Pain Relevance 0.10

General Comments

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