INT213959

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Context Info
Confidence 0.03
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.68
Pain Relevance 1.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Pax3) nucleus (Pax3) DNA binding (Pax3)
Anatomy Link Frequency
T cells 1
Pax3 (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 45 100.00 Very High Very High Very High
Neuropeptide 36 100.00 Very High Very High Very High
calcitonin gene related peptide 11 100.00 Very High Very High Very High
qutenza 5 99.20 Very High Very High Very High
trigeminal ganglion 75 90.76 High High
Somatostatin 20 89.12 High High
nociceptor 32 78.92 Quite High
Nav1.9 1 76.36 Quite High
nav1.8 1 75.64 Quite High
antagonist 5 75.20 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 85 90.76 High High
Targeted Disruption 45 85.12 High High
Pain 3 65.48 Quite High
Neurogenic Inflammation 2 61.80 Quite High
INFLAMMATION 11 23.44 Low Low
Hypersensitivity 2 13.76 Low Low
Nociception 3 9.52 Low Low
Repression 7 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, expression levels of mRNA for the Runx1-independent neuropeptides CGRP and Substance P/Tachykinin 1 (SP/Tac1) were little changed (Figure 3B), consistent with past results [16,17].
Transcription (levels) of SP associated with calcitonin gene related peptide, neuropeptide and substance p
1) Confidence 0.03 Published 2010 Journal Neural Dev Section Body Doc Link PMC2829025 Disease Relevance 0.54 Pain Relevance 1.10
Indeed, T cells have been shown to transcribe the mRNA for preprotachykinin A and release SP on activation with capsaicin [12].
Transcription (transcribe) of SP in T cells associated with qutenza and substance p
2) Confidence 0.02 Published 2001 Journal Respir Res Section Body Doc Link PMC2002076 Disease Relevance 0.15 Pain Relevance 0.44

General Comments

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