INT213965

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Context Info
Confidence 0.54
First Reported 2001
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 7
Total Number 9
Disease Relevance 4.18
Pain Relevance 1.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
macrophages 1
lymphocytes 1
Urine 1
rsm1 (Mus musculus)
Pain Link Frequency Relevance Heat
Somatostatin 34 100.00 Very High Very High Very High
fibrosis 4 92.32 High High
Peripheral nervous system 2 91.80 High High
Neuropeptide 64 84.08 Quite High
Calcitonin gene-related peptide 30 68.84 Quite High
abdominal pain 9 61.48 Quite High
substance P 84 46.40 Quite Low
qutenza 10 44.60 Quite Low
Inflammation 28 29.60 Quite Low
Bioavailability 3 6.60 Low Low
Disease Link Frequency Relevance Heat
Infection 94 100.00 Very High Very High Very High
Granuloma 4 100.00 Very High Very High Very High
Hepatitis 4 99.08 Very High Very High Very High
Acute Disease 12 98.90 Very High Very High Very High
Hepatitis C Virus Infection 4 96.84 Very High Very High Very High
Schistosomiasis 138 95.88 Very High Very High Very High
Nerve Root Compression 4 94.48 High High
Syndrome 76 94.12 High High
Malaria 40 93.28 High High
Cirrhosis 4 92.32 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In both cases, Schistosoma DNA was detectable in some but not all of the tested samples (data not shown).
Gene_expression (detectable) of Schistosoma
1) Confidence 0.54 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2667260 Disease Relevance 0.56 Pain Relevance 0
Several groups have developed polymerase chain reaction (PCR) methods to improve the direct detection of Schistosoma.
Gene_expression (detection) of Schistosoma
2) Confidence 0.47 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2667260 Disease Relevance 0.31 Pain Relevance 0
All of these patients had acute disease that was confirmed subsequently to be associated with Schistosoma infection.
Gene_expression (infection) of Schistosoma associated with acute disease and infection
3) Confidence 0.47 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2667260 Disease Relevance 0.74 Pain Relevance 0
Anti-Schistosoma antibodies can be detected by enzyme immunoassay (EIA), immunofluorescence assay (IFA), and indirect hemagglutination assay [15].
Gene_expression (detected) of Schistosoma
4) Confidence 0.42 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2667260 Disease Relevance 1.86 Pain Relevance 0.05
It will be interesting to evaluate the efficacy and safety of As+SMP on other Schistosoma species, such as Schistosoma mansoni, as well as the effect of the combination of As+SMP and PZQ on both S. haematobium and S. mansoni.


Gene_expression (mansoni) of Schistosoma
5) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2749939 Disease Relevance 0.21 Pain Relevance 0.06
It will be interesting to evaluate the efficacy and safety of As+SMP on other Schistosoma species, such as Schistosoma mansoni, as well as the effect of the combination of As+SMP and PZQ on both S. haematobium and S. mansoni.


Gene_expression (mansoni) of Schistosoma
6) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2749939 Disease Relevance 0.22 Pain Relevance 0.06
Urine samples were examined for Schistosoma haematobium on days ?
Spec (examined) Gene_expression (haematobium) of Schistosoma in Urine
7) Confidence 0.03 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2749939 Disease Relevance 0.09 Pain Relevance 0
Additional non-neuronal sources of somatostatin (such as granuloma cells within Schistosoma-induced liver granulomata, lymphocytes, macrophages and thymic DCs) have been described.
Gene_expression (sources) of Schistosoma-induced in macrophages associated with somatostatin and granuloma
8) Confidence 0.02 Published 2001 Journal Respir Res Section Body Doc Link PMC2002076 Disease Relevance 0.10 Pain Relevance 0.56
Additional non-neuronal sources of somatostatin (such as granuloma cells within Schistosoma-induced liver granulomata, lymphocytes, macrophages and thymic DCs) have been described.
Gene_expression (sources) of Schistosoma-induced in lymphocytes associated with somatostatin and granuloma
9) Confidence 0.01 Published 2001 Journal Respir Res Section Body Doc Link PMC2002076 Disease Relevance 0.10 Pain Relevance 0.56

General Comments

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