INT214011

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Ank1, Nav1) cytoplasm (Ank1, Nav1) cell differentiation (Nav1)
signal transduction (Ank1) plasma membrane (Ank1) nucleus (Ank1)
Ank1 (Mus musculus)
Nav1 (Mus musculus)
Pain Link Frequency Relevance Heat
sodium channel 2 99.48 Very High Very High Very High
Catecholamine 1 27.60 Quite Low
Somatostatin 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Heart Arrhythmia 1 99.44 Very High Very High Very High
Arrhythmia Under Development 22 97.20 Very High Very High Very High
Spherocytosis 1 77.72 Quite High
Aging 21 62.52 Quite High
Syndrome 8 61.04 Quite High
Myocardial Infarction 7 52.72 Quite High
Death 8 50.00 Quite Low
Bradycardia 3 43.52 Quite Low
Sudden Death 3 30.88 Quite Low
Alopecia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A cardiac voltage-gated sodium channel SCN5A human variant that abolishes binding of Nav1.5 with to ankyrin-G results in Brugada syndrome, which is a dominantly-inherited fatal cardiac arrhythmia [9].
Negative_regulation (abolishes) of ankyrin Binding (binding) of Nav1 associated with heart arrhythmia, sodium channel and arrhythmia under development
1) Confidence 0.01 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2013943 Disease Relevance 0.51 Pain Relevance 0.10

General Comments

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