INT214034

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Context Info
Confidence 0.53
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.85
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (APEX1) mitochondrion (APEX1) lyase activity (APEX1)
ribosome (APEX1) endoplasmic reticulum (APEX1) intracellular (APEX1)
Anatomy Link Frequency
brains 2
APEX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 1 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 126 99.84 Very High Very High Very High
Toxicity 2 66.80 Quite High
Targeted Disruption 1 61.68 Quite High
Aging 5 57.84 Quite High
Folic Acid Deficiency 1 50.96 Quite High
Neurodegenerative Disease 2 49.52 Quite Low
Apoptosis 2 47.12 Quite Low
Death 3 45.92 Quite Low
Cognitive Disorder 33 5.28 Low Low
Dementia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The finding that AP-site incision activity and APE1 protein levels were similar in brains of AD patients and controls differs from previous reports of increased APE1 expression in AD (13,14).
Positive_regulation (increased) of Gene_expression (expression) of APE1 in brains associated with disease
1) Confidence 0.53 Published 2007 Journal Nucleic Acids Research Section Body Doc Link PMC2018628 Disease Relevance 0.85 Pain Relevance 0

General Comments

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