INT214071

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Context Info
Confidence 0.37
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.77
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RARA) signal transduction (RARA) nucleus (RARA)
enzyme binding (RARA) transcription factor binding (RARA) cytoplasm (RARA)
RARA (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 87 78.84 Quite High
cytokine 12 23.28 Low Low
Inflammation 18 5.00 Very Low Very Low Very Low
rheumatoid arthritis 18 5.00 Very Low Very Low Very Low
Arthritis 11 5.00 Very Low Very Low Very Low
Potency 6 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 61 99.92 Very High Very High Very High
Cancer 79 98.40 Very High Very High Very High
Obesity 36 93.56 High High
Disease 7 87.52 High High
Rheumatoid Arthritis 38 85.92 High High
Esophageal Cancer 1 81.04 Quite High
Carcinoma 16 75.28 Quite High
Congenital Anomalies 1 67.28 Quite High
Body Weight 1 50.00 Quite Low
Hepatocellular Cancer 2 46.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
, the mRNA levels of RAR decreased from 30% to 55% for the -?
Negative_regulation (decreased) of Transcription (levels) of RAR
1) Confidence 0.37 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656246 Disease Relevance 0.09 Pain Relevance 0.07
Downregulation of mRNA expression of RAR?
Negative_regulation (Downregulation) of Transcription (expression) of RAR
2) Confidence 0.34 Published 2007 Journal Nutr J Section Body Doc Link PMC2018695 Disease Relevance 0.93 Pain Relevance 0
LBD impairs the transcriptional activity of RXR/RAR [21, 22] and RXR/vitamin D3 receptor (VDR) [23].
Negative_regulation (impairs) of Transcription (activity) of RAR
3) Confidence 0.23 Published 2008 Journal PPAR Research Section Body Doc Link PMC2408709 Disease Relevance 0.74 Pain Relevance 0

General Comments

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