INT214096

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Context Info
Confidence 0.76
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 0.62
Pain Relevance 1.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cartpt) extracellular region (Cartpt)
Anatomy Link Frequency
arcuate nucleus 1
afferent neurons 1
Cartpt (Mus musculus)
Pain Link Frequency Relevance Heat
Cholecystokinin 304 100.00 Very High Very High Very High
medulla 135 98.60 Very High Very High Very High
Locus ceruleus 7 88.68 High High
antagonist 59 87.76 High High
cocaine 15 81.60 Quite High
Kinase C 5 80.68 Quite High
analgesia 6 80.64 Quite High
Thalamus 4 65.44 Quite High
vagus nerve 14 61.84 Quite High
Central nervous system 30 56.72 Quite High
Disease Link Frequency Relevance Heat
Hyperphagia 6 92.36 High High
Anxiety Disorder 5 79.32 Quite High
Ganglion Cysts 3 77.28 Quite High
Eating Disorder 2 76.96 Quite High
Body Weight 12 65.44 Quite High
Aids-related Complex 17 60.36 Quite High
Stress 8 52.76 Quite High
Obesity 114 51.84 Quite High
Targeted Disruption 4 27.44 Quite Low
Syndrome 6 21.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Co-localization of CART peptide and CCK-A receptor in vagal afferent neurons suggested that CART peptide might take part in mediating satiety effects of cholecystokinin [23].
Localization (localization) of CART peptide in afferent neurons associated with cholecystokinin
1) Confidence 0.76 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2587474 Disease Relevance 0.28 Pain Relevance 0.88
Experiment 1 Individual and combined administration of CCK-8 and CART(61-102)
Localization (administration) of CART associated with cholecystokinin
2) Confidence 0.71 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2587474 Disease Relevance 0 Pain Relevance 0.14
The post hoc test showed a significant effect (P < 0.01) of parallel administration of CCK-8 and CART peptide on the Fos activation of cells in NTS in comparison with all other groups of animals (Fig. 3a, d).
Localization (administration) of CART peptide associated with medulla and cholecystokinin
3) Confidence 0.71 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2587474 Disease Relevance 0 Pain Relevance 0.55
POMC/CART and NPY/AgRP neuronal pathways from the arcuate nucleus
Localization (pathways) of CART in arcuate nucleus
4) Confidence 0.20 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.13 Pain Relevance 0.11
-MSH/CART release from arcuate neurones [152-154].
Localization (release) of CART
5) Confidence 0.20 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.21 Pain Relevance 0.13

General Comments

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