INT214119

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Context Info
Confidence 0.23
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.17
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lepr) extracellular space (Lepr) extracellular region (Lepr)
plasma membrane (Lepr)
Anatomy Link Frequency
autonomic 1
Lepr (Mus musculus)
Pain Link Frequency Relevance Heat
Autonomic response 2 94.00 High High
Action potential 4 83.40 Quite High
medulla 27 70.40 Quite High
vagus nerve 7 69.72 Quite High
Locus ceruleus 2 69.40 Quite High
Thalamus 2 68.12 Quite High
aspirin 56 5.00 Very Low Very Low Very Low
tolerance 30 5.00 Very Low Very Low Very Low
Central nervous system 17 5.00 Very Low Very Low Very Low
antagonist 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 1060 100.00 Very High Very High Very High
Hypoglycemia 136 98.70 Very High Very High Very High
Unconsciousness 8 98.36 Very High Very High Very High
Syndrome 11 97.80 Very High Very High Very High
Obesity 85 88.36 High High
Overweight 8 87.84 High High
Targeted Disruption 2 87.20 High High
Weight Loss 46 82.52 Quite High
Appetite Loss 16 81.84 Quite High
Emergencies 2 65.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The DMH is an important leptin target, as it expresses both leprb mRNA and protein [18,19].
Regulation (target) of leprb
1) Confidence 0.23 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.17 Pain Relevance 0.18
In addition to its role in preventing and controlling diabetes, ADA recognizes the importance of nutrition as an essential component of an overall healthy lifestyle.
Regulation (controlling) of diabetes associated with diabetes mellitus
2) Confidence 0.00 Published 2010 Journal Diabetes Care Section Body Doc Link PMC2797382 Disease Relevance 1.00 Pain Relevance 0
In type 1 diabetes and severely insulin-deficient type 2 diabetes, the syndrome of hypoglycemia unawareness, or hypoglycemia-associated autonomic failure, can severely compromise stringent diabetes control and quality of life.
Regulation (control) of diabetes in autonomic associated with hypoglycemia, syndrome, diabetes mellitus and unconsciousness
3) Confidence 0.00 Published 2010 Journal Diabetes Care Section Body Doc Link PMC2797382 Disease Relevance 2.00 Pain Relevance 0.05

General Comments

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