INT214129

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.36
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.21
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Mc3r) plasma membrane (Mc3r) signal transducer activity (Mc3r)
Anatomy Link Frequency
arcuate nucleus 2
Mc3r (Mus musculus)
Pain Link Frequency Relevance Heat
Cholecystokinin 16 94.56 High High
vagus nerve 14 60.72 Quite High
medulla 54 60.56 Quite High
Action potential 8 53.64 Quite High
Locus ceruleus 4 39.64 Quite Low
Thalamus 4 38.36 Quite Low
Central nervous system 30 10.48 Low Low
antagonist 20 5.00 Very Low Very Low Very Low
agonist 20 5.00 Very Low Very Low Very Low
amygdala 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Appetite Loss 20 81.08 Quite High
Obesity 114 73.52 Quite High
Targeted Disruption 4 57.44 Quite High
Hyperphagia 6 12.64 Low Low
Anorexia 28 5.00 Very Low Very Low Very Low
Sprains And Strains 10 5.00 Very Low Very Low Very Low
Weight Gain 8 5.00 Very Low Very Low Very Low
Stress 8 5.00 Very Low Very Low Very Low
Body Weight 6 5.00 Very Low Very Low Very Low
Syndrome 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Again, this may reflect indirect activation, perhaps via an arcuate nucleus POMC neuronal projection to the SON, as evidenced by immunocytochemical detection of POMC fibres between these nuclei and in situ hybridisation for MC3R in the arcuate nucleus and MC4R in the SON (Table 1; [90,93,118]).
Negative_regulation (detection) of Gene_expression (fibres) of MC3R in arcuate nucleus
1) Confidence 0.36 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.07 Pain Relevance 0.14
Despite the presence of the MC3R, only ?
Negative_regulation (Despite) of Gene_expression (presence) of MC3R
2) Confidence 0.36 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.14 Pain Relevance 0.09

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox