INT214139

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Context Info
Confidence 0.20
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.40
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Lep, Pomc) signal transduction (Lep, Pomc) extracellular region (Lep, Pomc)
intracellular (Lep) cell-cell signaling (Pomc) cytoplasm (Pomc)
Anatomy Link Frequency
CSF 2
Lep (Mus musculus)
Pomc (Mus musculus)
Pain Link Frequency Relevance Heat
Action potential 4 40.88 Quite Low
agonist 10 39.16 Quite Low
Central nervous system 15 23.32 Low Low
medulla 27 5.00 Very Low Very Low Very Low
antagonist 10 5.00 Very Low Very Low Very Low
Cholecystokinin 8 5.00 Very Low Very Low Very Low
amygdala 8 5.00 Very Low Very Low Very Low
gABA 8 5.00 Very Low Very Low Very Low
vagus nerve 7 5.00 Very Low Very Low Very Low
Nucleus accumbens 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 57 94.04 High High
Appetite Loss 10 72.16 Quite High
Anorexia 14 10.52 Low Low
Sprains And Strains 5 5.00 Very Low Very Low Very Low
Weight Gain 4 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low
Hyperphagia 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It should be noted that as leptin regulates POMC synthesis and release, it is difficult to dissect the role of POMC turnover in the CSF [122].

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leptin Regulation (regulates) of Localization (release) of POMC in CSF
1) Confidence 0.20 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.40 Pain Relevance 0

General Comments

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