INT214141

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Context Info
Confidence 0.32
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.82
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lep, Lepr) extracellular space (Lep, Lepr) extracellular region (Lep, Lepr)
plasma membrane (Lepr) intracellular (Lep) lipid metabolic process (Lep)
Lep (Mus musculus)
Lepr (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 10 64.40 Quite High
amygdala 8 61.36 Quite High
medulla 27 42.56 Quite Low
Thalamus 2 40.16 Quite Low
Nicotine 2 31.60 Quite Low
cocaine 3 30.68 Quite Low
Nucleus accumbens 5 18.92 Low Low
agonist 10 17.80 Low Low
Dopamine 1 10.68 Low Low
Central nervous system 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperphagia 3 91.76 High High
Syndrome 3 90.48 High High
Obesity 57 83.72 Quite High
Stress 4 62.44 Quite High
Thinness 2 58.96 Quite High
Anxiety Disorder 1 36.80 Quite Low
Aids-related Complex 1 27.56 Quite Low
Anorexia 14 7.52 Low Low
Appetite Loss 10 5.00 Very Low Very Low Very Low
Sprains And Strains 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Leptin binding to LEPRB is the main peripheral hormonal stimulus to arcuate POMC neurones [11] and SIM1 is specifically involved in the development of the PVN [185].
Leptin Binding (binding) of LEPRB
1) Confidence 0.32 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.82 Pain Relevance 0.12

General Comments

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