INT214143

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.20
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Lep, Pomc) signal transduction (Lep, Pomc) extracellular region (Lep, Pomc)
intracellular (Lep) cell-cell signaling (Pomc) cytoplasm (Pomc)
Anatomy Link Frequency
arcuate nucleus 1
brainstem 1
Lep (Mus musculus)
Pomc (Mus musculus)
Pain Link Frequency Relevance Heat
medulla 54 98.52 Very High Very High Very High
agonist 20 98.12 Very High Very High Very High
antagonist 20 87.96 High High
Central nervous system 30 67.28 Quite High
Cholecystokinin 16 5.00 Very Low Very Low Very Low
amygdala 16 5.00 Very Low Very Low Very Low
gABA 16 5.00 Very Low Very Low Very Low
vagus nerve 14 5.00 Very Low Very Low Very Low
Nucleus accumbens 10 5.00 Very Low Very Low Very Low
Somatostatin 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anorexia 28 96.96 Very High Very High Very High
Sprains And Strains 10 84.80 Quite High
Obesity 114 77.64 Quite High
Hyperphagia 6 41.52 Quite Low
Appetite Loss 20 10.64 Low Low
Weight Gain 8 5.00 Very Low Very Low Very Low
Stress 8 5.00 Very Low Very Low Very Low
Body Weight 6 5.00 Very Low Very Low Very Low
Syndrome 6 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Perhaps the MC4R receptor does integrate the anorexigenic signal from leptin via the POMC neurones of the arcuate nucleus and brainstem.
leptin Binding (integrate) of POMC in arcuate nucleus associated with medulla
1) Confidence 0.27 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.60 Pain Relevance 0.26
Perhaps the MC4R receptor does integrate the anorexigenic signal from leptin via the POMC neurones of the arcuate nucleus and brainstem.
leptin Binding (integrate) of POMC in brainstem associated with medulla
2) Confidence 0.09 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.60 Pain Relevance 0.26

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox