INT214145

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Context Info
Confidence 0.40
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Mc4r) extracellular space (Agrp) extracellular region (Agrp)
Golgi apparatus (Agrp) plasma membrane (Mc4r) signal transducer activity (Mc4r)
Agrp (Mus musculus)
Mc4r (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 15 98.08 Very High Very High Very High
antagonist 10 97.00 Very High Very High Very High
agonist 10 87.36 High High
Glutamate 1 85.44 High High
gABA 8 62.24 Quite High
medulla 27 5.00 Very Low Very Low Very Low
Cholecystokinin 8 5.00 Very Low Very Low Very Low
amygdala 8 5.00 Very Low Very Low Very Low
vagus nerve 7 5.00 Very Low Very Low Very Low
Nucleus accumbens 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anorexia 14 60.24 Quite High
Generalized Anxiety Disorder 2 60.04 Quite High
Obesity 57 48.92 Quite Low
Appetite Loss 10 5.00 Very Low Very Low Very Low
Sprains And Strains 5 5.00 Very Low Very Low Very Low
Weight Gain 4 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low
Hyperphagia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both AgRP and the MSHs can bind to MC3R and MC4R either presynaptically or postsynaptically [10,11].
AgRP Binding (bind) of MC4R
1) Confidence 0.40 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.18 Pain Relevance 0.37

General Comments

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