INT21415

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Context Info
Confidence 0.00
First Reported 1990
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 1.00

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cell-cell signaling (POMC, IL2) extracellular space (POMC, IL2) extracellular region (POMC, IL2)
small molecule metabolic process (POMC) cytoplasm (POMC) generation of precursor metabolites and energy (POMC)
Anatomy Link Frequency
NK cells 2
POMC (Homo sapiens)
IL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 9 100.00 Very High Very High Very High
opioid receptor 1 93.40 High High
Opioid 2 75.00 Quite High
Endogenous opioid 1 65.28 Quite High
Disease Link Frequency Relevance Heat
Aids-related Complex 3 82.56 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 68.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Methionine-enkephalin enhances the activity of NK cells and induces the production of IL-2, which in turn may recruit and activate other T-cell subsets like CD3 and CD4.
Methionine-enkephalin Positive_regulation (induces) of Gene_expression (production) of IL-2 in NK cells associated with enkephalin
1) Confidence 0.00 Published 1990 Journal NIDA Res. Monogr. Section Abstract Doc Link 2172824 Disease Relevance 0.27 Pain Relevance 1.00

General Comments

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