INT214153

Context Info Confidence 0.35 First Reported 2007 Last Reported 2007 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.15 Pain Relevance 0.06

Golgi apparatus (Nucb2) endoplasmic reticulum (Nucb2) intracellular (Lep) DNA binding (Nucb2) cytoplasm (Nucb2) lipid metabolic process (Lep)

Lep (Mus musculus) Nucb2 (Mus musculus)

Pain Link Frequency Relevance Heat antagonist 10 65.84 amygdala 8 53.08 medulla 27 5.00 Central nervous system 15 5.00 agonist 10 5.00 Cholecystokinin 8 5.00 gABA 8 5.00 vagus nerve 7 5.00 Nucleus accumbens 5 5.00 Somatostatin 4 5.00

Disease Link Frequency Relevance Heat Anorexia 14 85.60 Appetite Loss 10 62.00 Obesity 57 45.96 Targeted Disruption 2 44.56 Sprains And Strains 5 5.00 Weight Gain 4 5.00 Stress 4 5.00 Body Weight 3 5.00 Syndrome 3 5.00 Hyperphagia 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Central administration of leptin does not alter nucleobindin2/nesfatin mRNA expression.

leptin Neg (not) Regulation (alter) of Transcription (expression) of nesfatin

1) Confidence 0.35 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.15 Pain Relevance 0.06

General Comments

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