INT214156

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Context Info
Confidence 0.39
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pomc, Npy) extracellular region (Pomc, Npy) signal transduction (Pomc)
generation of precursor metabolites and energy (Pomc) cell-cell signaling (Pomc) cytoplasm (Pomc)
Pomc (Mus musculus)
Npy (Mus musculus)
Pain Link Frequency Relevance Heat
medulla 27 90.88 High High
vagus nerve 7 88.56 High High
Action potential 4 38.80 Quite Low
Locus ceruleus 2 24.80 Low Low
Thalamus 2 23.52 Low Low
Central nervous system 15 5.00 Very Low Very Low Very Low
antagonist 10 5.00 Very Low Very Low Very Low
agonist 10 5.00 Very Low Very Low Very Low
Cholecystokinin 8 5.00 Very Low Very Low Very Low
amygdala 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Appetite Loss 10 66.24 Quite High
Targeted Disruption 2 42.60 Quite Low
Obesity 57 5.00 Very Low Very Low Very Low
Anorexia 14 5.00 Very Low Very Low Very Low
Sprains And Strains 5 5.00 Very Low Very Low Very Low
Weight Gain 4 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low
Hyperphagia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This suggests that POMC may normally inhibit NPY expression tonically in the DMH and that AgRP may be a determinant of NPY release physiologically [161].
POMC Spec (may) Negative_regulation (inhibit) of Gene_expression (expression) of NPY
1) Confidence 0.39 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.07 Pain Relevance 0.09

General Comments

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