INT2142

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Context Info
Confidence 0.42
First Reported 1978
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 3.35
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Ptgir) signal transducer activity (Ptgir)
Anatomy Link Frequency
plasma 3
blood 1
blood cells 1
Ptgir (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 2 100.00 Very High Very High Very High
qutenza 1 100.00 Very High Very High Very High
antagonist 2 99.60 Very High Very High Very High
cINOD 2 95.36 Very High Very High Very High
ischemia 3 94.76 High High
Angina 3 93.48 High High
aspirin 2 87.76 High High
Disease Link Frequency Relevance Heat
Muscular Spasm 3 99.28 Very High Very High Very High
Hypertension 3 99.04 Very High Very High Very High
Overactive Bladder 3 98.48 Very High Very High Very High
Coronary Artery Disease 24 97.96 Very High Very High Very High
INFLAMMATION 1 93.92 High High
Cv General 3 Under Development 3 93.48 High High
Pressure And Volume Under Development 2 84.44 Quite High
Natriuresis 6 83.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effects of the selective prostacyclin receptor antagonist RO3244019 on the micturition reflex in rats.
Regulation (Effects) of prostacyclin associated with qutenza, antagonist and overactive bladder
1) Confidence 0.42 Published 2007 Journal J. Urol. Section Title Doc Link 17945281 Disease Relevance 0.19 Pain Relevance 0.20
Because ANP and PGI2 are vasoactive peptides which regulate vasomotion, there must be an interaction between steroidogenesis hormones and vasoactive peptides.
Regulation (regulate) of PGI2
2) Confidence 0.29 Published 1993 Journal Chin. Med. Sci. J. Section Abstract Doc Link 8032065 Disease Relevance 0.94 Pain Relevance 0.14
We evaluated the effects of androgen (Sustanon 250) administration on plasma ANP, PGI2 and thromboxane (TXA2) levels in elderly men with CHD.
Regulation (effects) of PGI2 in plasma associated with coronary artery disease
3) Confidence 0.26 Published 1993 Journal Chin. Med. Sci. J. Section Abstract Doc Link 8032065 Disease Relevance 1.01 Pain Relevance 0.13
Influence of prostacyclin on regional blood flow distribution in anesthetized dogs.
Regulation (Influence) of prostacyclin in blood associated with anesthesia
4) Confidence 0.21 Published 1982 Journal Arch Int Pharmacodyn Ther Section Title Doc Link 6762168 Disease Relevance 0 Pain Relevance 0.10
Our findings demonstrate that androgen exerts its regulatory role by altering plasma ANP levels and the TXA2/PGI2 ratio.
Regulation (altering) of PGI2 in plasma
5) Confidence 0.13 Published 1993 Journal Chin. Med. Sci. J. Section Abstract Doc Link 8032065 Disease Relevance 0.76 Pain Relevance 0.08
Antihypertensive effect of prostacyclin (PGI2) in experimental hypertension and its influence on plasma renin activity in rats.
Regulation (effect) of prostacyclin in plasma associated with anesthesia and hypertension
6) Confidence 0.12 Published 1978 Journal Prostaglandins Med Section Title Doc Link 364507 Disease Relevance 0.35 Pain Relevance 0.10
Prostacyclin (PGI2) and prostaglandin (PG)E2, dominant products of COX activityin macro- and microvascular endothelial cells, respectively, in vitro, modulate the interaction of blood cells with the vasculature and contribute to the regulation of blood pressure.
Regulation (regulation) of Prostacyclin in blood cells
7) Confidence 0.01 Published 2006 Journal Handb Exp Pharmacol Section Abstract Doc Link 16999220 Disease Relevance 0.09 Pain Relevance 0.27

General Comments

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