INT214235

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Context Info
Confidence 0.34
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 3.50
Pain Relevance 1.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CDSN) cell adhesion (CDSN)
CDSN (Homo sapiens)
Pain Link Frequency Relevance Heat
psoriasis 6 99.04 Very High Very High Very High
spinal inflammation 50 96.80 Very High Very High Very High
Multiple sclerosis 96 95.32 Very High Very High Very High
rheumatoid arthritis 100 95.04 Very High Very High Very High
Central nervous system 2 78.80 Quite High
Inflammation 10 70.80 Quite High
Crohn's disease 26 21.64 Low Low
Arthritis 14 5.00 Very Low Very Low Very Low
imagery 12 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Psoriasis 6 99.04 Very High Very High Very High
Disease 296 97.96 Very High Very High Very High
Diabetes Mellitus 68 97.54 Very High Very High Very High
Low Back Pain 50 96.80 Very High Very High Very High
Demyelinating Disease 100 95.32 Very High Very High Very High
Rheumatoid Arthritis 114 95.04 Very High Very High Very High
Schizophrenia 172 93.88 High High
Genetic Predisposition To Disease 4 86.92 High High
Autoimmune Disease 106 83.24 Quite High
Rheumatic Diseases 2 73.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Those include polymorphisms in HLA-B associated transcript 3 (BAT3), E74-like factor 1 (ELF1), HLA-DMB, VARS2, BTNL2, TRIM40, ZSCAN23 and CDSN.
CDSN Binding (associated) of
1) Confidence 0.34 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2791168 Disease Relevance 1.84 Pain Relevance 0.98
While mutations in this gene have been previously associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and Grave’s Disease [28]–[30], the inverse allelic relationship has not been previously recognized. rs1265048 falls near CDSN and PSORS1C1 both of which have previously been associated with susceptibility to psoriasis [31],[32]. rs151719 falls in HLA-DMB, an MHC class II molecule that has been previously associated with T1D [33].
CDSN Binding (associated) of associated with psoriasis, spinal inflammation, diabetes mellitus and disease
2) Confidence 0.30 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2791168 Disease Relevance 1.22 Pain Relevance 0.17
According to our findings, the severity of both positive and negative symptoms directly correlates with the S-increase within the hyper-synchronized temporal clusters and in their neighborhood (cf.
S-increase Binding (correlates) of
3) Confidence 0.02 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2020441 Disease Relevance 0.45 Pain Relevance 0
As follows from its mathematical definition, the values of the S-estimator are bounded within the interval [0,1], and thus they cannot be normally distributed.
S-estimator Binding (bounded) of
4) Confidence 0.02 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2020441 Disease Relevance 0 Pain Relevance 0

General Comments

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