INT21425

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Context Info
Confidence 0.01
First Reported 1990
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 1.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pomc, Gtpbp4) Golgi apparatus (Gtpbp4) GTPase activity (Gtpbp4)
ribosome biogenesis (Gtpbp4) cell-cell signaling (Pomc) extracellular space (Pomc)
Pomc (Rattus norvegicus)
Gtpbp4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 7 99.80 Very High Very High Very High
Dynorphin 7 99.42 Very High Very High Very High
Opioid 7 92.56 High High
narcan 3 89.44 High High
antagonist 1 85.84 High High
opioid receptor 1 85.40 High High
tetrodotoxin 1 73.24 Quite High
Disease Link Frequency Relevance Heat
Bordatella Infection 2 98.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Preincubation with pertussis toxin prevented the lithium stimulation of dynorphin and Met-enkephalin, but not beta-endorphin, release, indicating lithium interacts with a G-protein to affect the autoreceptor controlling the release of dynorphin and Met-enkephalin.
beta-endorphin Binding (interacts) of G-protein associated with bordatella infection, dynorphin and enkephalin
1) Confidence 0.01 Published 1990 Journal Neuroscience Section Abstract Doc Link 2172862 Disease Relevance 0.10 Pain Relevance 1.45

General Comments

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