INT214361

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Context Info
Confidence 0.28
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Amph) cytoplasm (Amph)
Anatomy Link Frequency
brain 2
Amph (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 103 91.28 High High
Eae 2 87.84 High High
Catecholamine 1 67.92 Quite High
addiction 2 29.16 Quite Low
Opioid 1 28.72 Quite Low
tolerance 1 28.08 Quite Low
alcohol 1 27.68 Quite Low
cocaine 4 26.56 Quite Low
imagery 5 14.08 Low Low
Neurotransmitter 2 8.20 Low Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 6 91.84 High High
Opiate Addiction 1 29.16 Quite Low
Apoptosis 1 21.48 Low Low
Drug Dependence 2 5.00 Very Low Very Low Very Low
Amphetamine Dependence 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Manic Depressive Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
cells by STZ in rats is a model of insulin depletion, and as such, we hypothesized that PI3K signaling in the brain, as well as DAT cell surface expression and possibly DAT-mediated behavioral effects of AMPH, would be reduced following STZ pretreatment.
Negative_regulation (reduced) of Gene_expression (expression) of AMPH in brain
1) Confidence 0.28 Published 2007 Journal PLoS Biology Section Body Doc Link PMC2020502 Disease Relevance 0.09 Pain Relevance 0.35

General Comments

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