INT214367

Context Info Confidence 0.01 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.21

cytoplasm (Amph, Ubqln1) endoplasmic reticulum (Ubqln1) nucleus (Ubqln1) cytoskeleton (Amph) protein complex (Ubqln1)

Anatomy Link Frequency striatum 2 Amph (Rattus norvegicus) Ubqln1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Dopamine 103 100.00 imagery 5 88.64 cocaine 4 5.00 Ventral tegmentum 3 5.00 midbrain 2 5.00 Eae 2 5.00 Neurotransmitter 2 5.00 addiction 2 5.00 isoflurane 2 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Diabetes Mellitus 6 25.00 Amphetamine Dependence 1 25.00 Drug Dependence 2 5.00 Opiate Addiction 1 5.00 Apoptosis 1 5.00 Congenital Anomalies 1 5.00 Attention Deficit Hyperactivity Disorder 1 5.00 Decapitation 1 5.00 Depression 1 5.00 Manic Depressive Disorder 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Finally, local infusion of insulin into the striatum of STZ-treated animals significantly recovers the ability of AMPH to stimulate DA release as measured by high-speed chronoamperometry.

AMPH Positive_regulation (stimulate) of Localization (release) of DA in striatum associated with dopamine

1) Confidence 0.01 Published 2007 Journal PLoS Biology Section Abstract Doc Link PMC2020502 Disease Relevance 0 Pain Relevance 0.21

General Comments

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