INT214374

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Context Info
Confidence 0.37
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Slc6a3) transmembrane transport (Slc6a3) cytoplasm (Pik3cb)
cytosol (Pik3cb) signal transduction (Pik3cb) cell adhesion (Pik3cb)
Anatomy Link Frequency
plasma 2
Pik3cb (Rattus norvegicus)
Slc6a3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 103 100.00 Very High Very High Very High
addiction 2 99.60 Very High Very High Very High
Neurotransmitter 2 97.72 Very High Very High Very High
Ventral tegmentum 3 52.44 Quite High
Eae 2 51.68 Quite High
Nucleus accumbens 1 41.48 Quite Low
imagery 5 5.00 Very Low Very Low Very Low
cocaine 4 5.00 Very Low Very Low Very Low
midbrain 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Dependence 2 99.60 Very High Very High Very High
Diabetes Mellitus 6 81.76 Quite High
Appetite Loss 1 55.84 Quite High
Opiate Addiction 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Amphetamine Dependence 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regulation of DAT plasma membrane expression (and subsequently of extracellular DA) by PI3K signaling is emerging as an important mechanism linking neurotransmitter transporter function to psychomotor stimulant abuse [11,13].
PI3K Regulation (Regulation) of Gene_expression (expression) of DAT in plasma associated with neurotransmitter and dopamine
1) Confidence 0.37 Published 2007 Journal PLoS Biology Section Body Doc Link PMC2020502 Disease Relevance 0.30 Pain Relevance 0.35

General Comments

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