INT214464

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Context Info
Confidence 0.34
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.95
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd44) Golgi apparatus (Cd44) plasma membrane (Cd44)
nucleus (Cd44) protein complex (Cd44) cytoplasm (Cd44)
Anatomy Link Frequency
T cells 2
Cd44 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 6 99.84 Very High Very High Very High
Spinal cord 2 93.12 High High
cytokine 9 71.20 Quite High
imagery 25 50.00 Quite Low
dexamethasone 22 5.00 Very Low Very Low Very Low
Multiple sclerosis 17 5.00 Very Low Very Low Very Low
Inflammation 12 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 5 100.00 Very High Very High Very High
Central Nervous System Disease 6 99.84 Very High Very High Very High
Apoptosis 38 99.82 Very High Very High Very High
Metastasis 51 98.28 Very High Very High Very High
Disease 13 97.16 Very High Very High Very High
Colon Cancer 43 94.40 High High
Multiple Sclerosis 50 87.92 High High
Immunization 2 84.00 Quite High
Cancer 86 70.80 Quite High
Death 15 69.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In parallel, to test whether VT680 activates cells in vivo, we measured levels of CD25 and CD44 expression on Thy1.2 (VT680+) and Thy1.1 (unstained) cells (Fig. 1J).
Regulation (levels) of Gene_expression (expression) of CD44
1) Confidence 0.34 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2034600 Disease Relevance 0.17 Pain Relevance 0.04
However, neither the level of apoptosis nor the expression of cell adhesion molecules such as LFA-1 and CD44 were altered in CNS-infiltrating T cells (Fig. 6A and data not shown).
Neg (nor) Regulation (altered) of Gene_expression (expression) of CD44 in T cells associated with central nervous system, apoptosis and adhesions
2) Confidence 0.31 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2781169 Disease Relevance 1.16 Pain Relevance 0.14
Although multiple markers, such as CD10, CD44, VEGF, TGF-?
Regulation (Although) of Gene_expression (markers) of CD44
3) Confidence 0.21 Published 2010 Journal J Transl Med Section Body Doc Link PMC2841127 Disease Relevance 1.62 Pain Relevance 0

General Comments

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