INT214571

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 8
Disease Relevance 7.77
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CD27)
Anatomy Link Frequency
B-cell 2
CD27 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 8 43.28 Quite Low
Inflammation 16 20.72 Low Low
Arthritis 8 5.00 Very Low Very Low Very Low
abdominal pain 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 216 100.00 Very High Very High Very High
Systemic Lupus Erythematosus 504 99.72 Very High Very High Very High
Infection 32 99.30 Very High Very High Very High
Autoimmune Disease 32 95.72 Very High Very High Very High
Bacterial Infection 136 93.76 High High
Syndrome 16 91.12 High High
Systemic Sclerosis 8 90.08 High High
Opportunistic Infections 8 83.96 Quite High
Congenital Anomalies 24 67.76 Quite High
Necrosis 8 62.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Within the group of SLE patients, the presence of serum anti-RNP antibodies (N = 13) was found to be associated with a higher frequency of CD27++/CD20?
Positive_regulation (frequency) of Gene_expression (/) of CD27 associated with systemic lupus erythematosus
1) Confidence 0.49 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.30 Pain Relevance 0
Increased mean frequencies of CD27++/CD20?
Positive_regulation (Increased) of Gene_expression (frequencies) of CD27
2) Confidence 0.49 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.68 Pain Relevance 0
SLE patients showed increased frequencies of CD27++/CD20?
Positive_regulation (frequencies) of Gene_expression (/) of CD27 associated with systemic lupus erythematosus
3) Confidence 0.49 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.48 Pain Relevance 0
In support, we found that two newly diagnosed SLE patients admitted to our hospital due to an elevated disease activity had strongly elevated CD27++ PC numbers that persisted during their hospital stay.
Positive_regulation (elevated) of Gene_expression (numbers) of CD27 associated with disease and systemic lupus erythematosus
4) Confidence 0.49 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 1.46 Pain Relevance 0
On admission (day 0), both SLE patients had elevated frequencies and absolute numbers of CD27++/CD20?
Positive_regulation (elevated) of Gene_expression (frequencies) of CD27 associated with systemic lupus erythematosus
5) Confidence 0.49 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.93 Pain Relevance 0
Indeed, polyclonal B-cell activation due to infection could be considered as a possible cause of CD27++ PC expansion.
Spec (possible) Positive_regulation (cause) of Gene_expression (expansion) of CD27 in B-cell associated with infection
6) Confidence 0.49 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 1.51 Pain Relevance 0
In support, we found that two newly diagnosed SLE patients admitted to our hospital due to an elevated disease activity had strongly elevated CD27++ PC numbers that persisted during their hospital stay.
Positive_regulation (elevated) of Gene_expression (numbers) of CD27 associated with disease and systemic lupus erythematosus
7) Confidence 0.49 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 1.48 Pain Relevance 0
Patients with systemic lupus erythematosus (SLE) exhibit an expanded population of CD27++ PCs, while the number of CD27?
Positive_regulation (number) of Gene_expression (number) of CD27 associated with systemic lupus erythematosus
8) Confidence 0.49 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.93 Pain Relevance 0

General Comments

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