INT214609

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Context Info
Confidence 0.08
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 1.78
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (FOXC1) nucleus (FOXC1) DNA binding (FOXC1)
transcription factor binding (FOXC1) cytoplasm (FOXC1)
Anatomy Link Frequency
enterocytes 2
FOXC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 200 94.28 High High
Inflammation 170 91.92 High High
agonist 60 70.88 Quite High
chemokine 10 46.00 Quite Low
Crohn's disease 35 36.12 Quite Low
Inflammatory mediators 5 14.64 Low Low
Inflammatory response 10 6.80 Low Low
dexamethasone 35 5.00 Very Low Very Low Very Low
corticosteroid 10 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 175 91.92 High High
Inflammatory Bowel Disease 160 82.52 Quite High
Disease 40 75.76 Quite High
Recurrence 10 66.36 Quite High
Targeted Disruption 5 61.20 Quite High
Necrosis 5 60.04 Quite High
Cancer 5 59.68 Quite High
Mucositis 5 49.12 Quite Low
Adhesions 10 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and GRO), while others were higher expressed after ARA (MCP-1, and angiogenin).
Positive_regulation (higher) of Gene_expression (expressed) of ARA
1) Confidence 0.08 Published 2007 Journal Lipids Section Body Doc Link PMC2039812 Disease Relevance 0.71 Pain Relevance 0.25
This indicates that the increased basal PGE2 production by ARA cannot explain the different effects of ARA and EPA on NF-?
Positive_regulation (increased) of Gene_expression (production) of ARA
2) Confidence 0.07 Published 2007 Journal Lipids Section Body Doc Link PMC2039812 Disease Relevance 0 Pain Relevance 0.15
B activation and ICAM-1 expression as compared to ARA indeed showed that EPA and ARA differently affected the NF-?
Positive_regulation (activation) of Gene_expression (showed) of ARA
3) Confidence 0.07 Published 2007 Journal Lipids Section Body Doc Link PMC2039812 Disease Relevance 0.22 Pain Relevance 0.24
Because EPA and OA resulted in comparable changes in the proportions of ARA in the phospholipids of the enterocytes, the reported effects may be ascribed to the increased ARA proportion in the ARA cultured cells.
Positive_regulation (increased) of Gene_expression (proportion) of ARA in enterocytes
4) Confidence 0.07 Published 2007 Journal Lipids Section Body Doc Link PMC2039812 Disease Relevance 0.63 Pain Relevance 0.12
B activation and ICAM-1 expression as compared to ARA indeed showed that EPA and ARA differently affected the NF-?
Positive_regulation (indeed) of Gene_expression (showed) of ARA
5) Confidence 0.07 Published 2007 Journal Lipids Section Body Doc Link PMC2039812 Disease Relevance 0.22 Pain Relevance 0.24

General Comments

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