INT214707

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Context Info
Confidence 0.24
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.76
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc2a8) transmembrane transporter activity (Slc2a8) plasma membrane (Slc2a8)
transmembrane transport (Slc2a8)
Anatomy Link Frequency
endothelial cells 1
cerebral cortex 1
Slc2a8 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 11 99.48 Very High Very High Very High
cerebral cortex 12 98.80 Very High Very High Very High
medulla 27 91.84 High High
Inflammation 31 88.96 High High
withdrawal 1 88.08 High High
positron emission tomography 84 82.96 Quite High
Inflammatory response 7 79.68 Quite High
Spinal cord 17 77.84 Quite High
midbrain 13 63.88 Quite High
imagery 97 57.40 Quite High
Disease Link Frequency Relevance Heat
Cancer 415 99.72 Very High Very High Very High
Targeted Disruption 120 99.54 Very High Very High Very High
Malignant Neoplastic Disease 15 99.40 Very High Very High Very High
Necrosis 9 92.24 High High
INFLAMMATION 38 88.96 High High
Hypoxia 3 80.92 Quite High
Squamous Cell Neoplasms 15 75.00 Quite High
Disease 196 50.00 Quite Low
Dementia 17 50.00 Quite Low
Paralysis 13 22.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In search for the signs of BBB damage in the brain of symptomatic A53T mice, we examined the expression and subcellular distribution of aquaporin 4, glucose transporter 1 (Glut1) and von Willebrand factor (vWF) in astrocyte and vascular endothelial cells.
Spec (examined) Gene_expression (expression) of glucose transporter 1 in endothelial cells associated with targeted disruption
1) Confidence 0.24 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 0.45 Pain Relevance 0.26
However, GLUT8 is expressed only in the hippocampus, the cerebral cortex and the hypothalamus [61-63].
Gene_expression (expressed) of GLUT8 in cerebral cortex associated with hippocampus and cerebral cortex
2) Confidence 0.21 Published 2010 Journal The Open Biochemistry Journal Section Body Doc Link PMC2864432 Disease Relevance 0.08 Pain Relevance 0.14
Compared to the control group, high levels—though not statistically significant—of glucose transporter-1, HK II, and Ki67 expression were found at the end of treatment in both FDG and FLT groups.
Gene_expression (expression) of glucose transporter-1
3) Confidence 0.14 Published 2007 Journal Mol Imaging Biol Section Body Doc Link PMC2040178 Disease Relevance 0.61 Pain Relevance 0.04
All tumors demonstrated expression of glucose transporter-1, thymidine kinase-1, and hexokinase II.
Gene_expression (expression) of glucose transporter-1 associated with cancer
4) Confidence 0.11 Published 2007 Journal Mol Imaging Biol Section Abstract Doc Link PMC2040178 Disease Relevance 0.83 Pain Relevance 0.16
This entire process is thought to occur more readily in malignant cells than in normal cells due to the overexpression of the glucose transporters GLUT 1 and GLUT 3 by malignant cells and due to higher levels of hexokinase within malignant cells.
Gene_expression (overexpression) of glucose transporters GLUT 1 associated with malignant neoplastic disease
5) Confidence 0.02 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.79 Pain Relevance 0

General Comments

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