INT214890

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (GOPC, CDKN1A) cytosol (CDKN1A) nucleoplasm (CDKN1A)
Golgi apparatus (GOPC) nucleus (CDKN1A) plasma membrane (GOPC)
Anatomy Link Frequency
proximal 1
GOPC (Homo sapiens)
CDKN1A (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 32 89.36 High High
Cyst 21 75.76 Quite High
Cancer 10 70.88 Quite High
Stress 1 52.92 Quite High
Polycystic Kidney Disease 36 50.00 Quite Low
Disease 26 19.84 Low Low
Renal Disease 3 16.40 Low Low
Chronic Renal Failure 3 12.56 Low Low
Cystic Kidney Diseases 6 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with our model of p21 decrease being associated with the cystic phenotype, we found that p21 was induced in a dose dependent fashion by roscovitine (Fig. 7), suggesting a mechanism for the roscovitine effect proximal to cyclin-cdk inhibition.
Fig Positive_regulation (induced) of p21 in proximal
1) Confidence 0.06 Published 2007 Journal BMC Nephrol Section Body Doc Link PMC2045080 Disease Relevance 0.57 Pain Relevance 0

General Comments

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