INT214909

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (PRKD1) small molecule metabolic process (PRKD1) Golgi apparatus (PRKD1)
cytoplasm (PRKD1) cytosol (PRKD1) cell proliferation (PRKD1)
PRKD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 32 99.24 Very High Very High Very High
Cancer 10 90.00 High High
Cyst 21 69.36 Quite High
Polycystic Kidney Disease 36 50.00 Quite Low
Stress 1 46.52 Quite Low
Disease 26 28.96 Quite Low
Renal Disease 3 25.52 Quite Low
Chronic Renal Failure 3 21.68 Low Low
Cystic Kidney Diseases 6 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since PKD is associated with increase RTE apoptosis[2] and p21 possesses an anti-apoptotic function in several cell lines [5,21], we would expect potential drug therapies for PKD to not be associated with programmed cell death, in contrast to what would be expected in the cancer chemotherapy setting [24].
PKD Binding (associated) of associated with cancer and apoptosis
1) Confidence 0.04 Published 2007 Journal BMC Nephrol Section Body Doc Link PMC2045080 Disease Relevance 0.58 Pain Relevance 0

General Comments

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