INT214913

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.08
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.47
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Tp53) mitochondrion (Tp53) aging (Tp53)
endoplasmic reticulum (Tp53) enzyme binding (Tp53) protein complex assembly (Tp53)
Anatomy Link Frequency
fibroblasts 2
Tp53 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 19 50.00 Quite Low
Inflammatory marker 2 15.60 Low Low
adenocard 5 5.00 Very Low Very Low Very Low
withdrawal 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 4 99.84 Very High Very High Very High
Autism 82 99.12 Very High Very High Very High
Apoptosis 33 97.20 Very High Very High Very High
Disease Progression 4 96.00 Very High Very High Very High
Cerebral Hypoxia 1 95.40 Very High Very High Very High
Stress 40 92.28 High High
Disease 27 87.32 High High
Polycystic Kidney Disease 36 84.16 Quite High
Renal Disease 3 76.88 Quite High
Cystic Kidney Diseases 6 70.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Elevated p53 is induced by hypoxia [72] and a decrease in Bcl-2 is associated with increased apoptosis provoked by hypoxia [73].
Positive_regulation (induced) of Positive_regulation (Elevated) of p53 associated with hypoxia and apoptosis
1) Confidence 0.08 Published 2007 Journal BMC Pediatr Section Body Doc Link PMC2244616 Disease Relevance 1.71 Pain Relevance 0
Our data is supported by another study demonstrating that immortalized proliferation of mouse embryonic fibroblasts from PKD1(-/-) mice occurs without the induction of p53 and (at late passage) p21 [28], as well a study showing that the CDK inhibitor roscovitine arrests disease progression[10].
Positive_regulation (occurs) of Neg (without) Positive_regulation (induction) of p53 in fibroblasts associated with disease progression
2) Confidence 0.04 Published 2007 Journal BMC Nephrol Section Body Doc Link PMC2045080 Disease Relevance 0.75 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox